Epitalon
Ala-Glu-Asp-Gly tetrapeptide studied in pineal / melatonin-rhythm, telomere, and aging research.
Overview
Epitalon (also written Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on the pineal peptide epithalamin.
It is studied in circadian, pineal-function, telomere, and aging research models — typically in short courses rather than continuous use, framed around restoring melatonin rhythm.
Mechanism of interest
- Pineal signalling — studied for supporting a normal melatonin curve (strong at night, clean morning drop) in research models.
- Telomere research — investigated in cell studies for effects on telomerase activity.
- Short-course framing — characterized in the literature as a periodic rather than continuous signal.
Research areas
Handling & storage
- Lyophilized powder. Store sealed vials at -20°C, protected from light.
- Reconstitute with bacteriostatic water; refrigerate at 2–8°C after reconstitution.
- Avoid repeated freeze/thaw cycles.
Selected references
- 1.Khavinson VK, et al. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003.
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